NO MORE DRUGS FOR THESE GUYS. When we took him in, the nurse noticed bumps on his back and the vet (a new one) decides that it is a skin infection and prescribes(without permission) Cefpodoxime and Apoquel. Thanks to all for yoru comments. However, it is not recommended that you do so. Zoetis and veterinarians should be held accountable, how can you be killing dogs with no compassion , no ethics, no nothing. I WOULD NOT recommend giving Apoquel to your pet!! Monitor your dog for any symptoms. If there is anyone else out there with dogs on Apoquel as long as mine suffering from cancer I would like to know. DO NOT GIVE THIS POISON TO YOUR PET. I dont trust drugs and I dont trust doctors, or car sales men, or lawyers for that matter. Thanks! My vet bills have double. One pill thats all she got! Ive been searching all day and came across other dogs doing the same. As a result, hydroxyzine pamoate is what doctors will prescribe to human patients to treat anxiety. Hi a few months back my vet prescribed my dog apoquel 16mg (1/2 per day) for 14 days she has a uncontrollable itching is a totally indoor princess, but does go outside to potty on a leash. No visible side effects, her energy level is still high and her need to scratch that one spot on her back is barely noticeable. Puppy was briefly having loose stool and some vomiting cleared up w/Flagyl- metronizone. I watch the Zeljanz commercial which is basically a very similar drug for humans.listening to all the huge long list of potential side effects.cancers have happened and they say it like potential for thunderstormslike no big deal. But, we are seeing improvementfinally. Some of the horror stories above are frightening. He was a totally healthy dog before Apoquel! My 5 year ol shi tzu terrier mix has terrible allergies that caused her to itch 24/7. Does anyone else experience these symptoms? Anorexia was the only adverse event noted more often Its crazy how fast that can happen. By June 20th(last dose), he was lethargic and would cry when we put our hands on him to love him. Benadryl wasnt working so Dr. prescribed Apoquel 6/9/2016. In fact, antihistamines are quite often used to treat skin allergies in dogs. Now, just do the rest of the world a favor and drop off the face of it and stop trying to scare people into doing what you want and believing what you think is correct. In simple terms, apoquel changes how the immune system acts. She gave my dog Prince Si Miao Four Marvels Formula (can buy this online) I gave a 1/4 or less amount that a human would take for 4 months (herbs must be watched not to take for long periods of time so look for any side effects like blood in stool) . Does that sound about right? Additionally, our dogs eyes have been filling with a night green mucus. Hydroxyzine for dogs is known to interact with other medications. Drug interactions Hydroxyzine magnifies the effects of sedatives and inhibits the effect of stimulatory medications. Hello Dr I criticize but choose not to use my real name, This article is 100% based on FDA Veterinary ADE reports- you may want to visit the FDA site and read the stats for yourself. Im going to discontinue and if the itching returns, begin with 1/2 the recommended dose. It's . He has lost 1 1/2 lbs. If worse I will probably take her off it. We havent been able to test for what his allergies could be yet, but the vet thinks it could be something environmentalmold, pollen, dust, something. Started my dog on on this medicine 6 days ago. Initially, his itching nearly subsided after staring Apoquel however, not for long. He has always had allergies, some seasons are worse than others. This drug may stop your dogs itching, however creating long I would have preferred using prednisone as it has worked well in the past and he didnt need to take much. IV or liposomal? They have been developed so as not to cause drowsiness. Stupid meI passed it off as a fluke. Her liver enzymes, glucose reading were off the charts. Apoquel side effects listed for dogs in the product insert include: vomiting, diarrhea, lethargy, anorexia, SQ or dermal masses (unspecified), decreased leukocytes, decreased globulins, and increased cholesterol and lipase. In December 2017 we again returned to the veterinary center for evaluation and suggestions regarding these growths which continued to increase in number. dog? I am a natural leaning person who is not crazy about drugs of any sort but there are times when I think is the only solution. Am going to phone my vet in the morning and get their opinion. They would do this if it was drug which had these effects on humans. It is disturbing to realize that others have had almost the same situation. These past 6 months have been H-ll with our beloved pets on these dangerous medications. for severe Gastro-Intestinal issues. She set up an appt. and chemistry). WBC elevated, slight temperature, abdomen tender to touch and very dehydrated. Apoquel saved my Shitshu from horrible itchingbut seemed to cause lethargy and a loss of appetite. I have never seen him like that so I wont be giving him the medication anymore. All of the sudden it clicked. I stoped it todayim terrified. Im always sceptical of new drugs and wish I had just said no to Apoquel. He was a healthy and playful boy and certainly did not act his age!!! I have tried many things and 3 Vets, also already two operations. Ahh me Read all the reviews on this page!! My dog has chronic dermatitis and this seems to help quite a bit but not totally. Lets see the drug company Zoetis reported this: Zoetis Reports Fourth Quarter and Full Year 2014 Results He had to have the dosage raised today after 2 seizures this morning. I was also giving him baths with malaseb or microtek shampoo every few days. Assuming you are a veterinarian, you may want to consider being slightly more professional in your communication Instead of taking the heat, paying what you owe for flapping your gums when you said you wouldnt, you took the easy way out. Here are 5 natural alternatives to apoquel for dogs you can try: 1. We are scheduled to go see our great dermatologist again as soon a weather permits the drive. When we moved my new vet recommended the new drug that was having great results on allergies in dogs Apoquel. And I know she picked the profession she did because of a passion for animals. What are the side effects of hydroxyzine in dogs? Wow my eyes are wide. Vet in the practice, (not her regular vet) approached me in the lobby and said she had a drug that would stop her allergies. Tried Benydry but it only made him groggy. I noticed that she did have some more frequent urination and she had a kind of balance issue, she just wasnt acting right when she first started on the apoquel. He is a cocker spaniel who is now just over 10 years old. Any one with me? The mission is integrative and functional. BUT 2 days ago he has started having breathing problemsnever had that before. I certainly cant say for sure that the Apoquel caused this tumor but am quite confident that it probably exacerbated it. Dogs have 10 times more mast cells on their skin than people do. On the fourth day he started vomiting and having diarrhea. Apoquel is an allergy medication while Benadryl is an antihistamine. On top of all of this, it appears she is suddenly going blind she bumps into things, walks into things cannot see her water and wont drink out of her bowls. His previous blood tests (before Apoquel) were normal. I am taking him to the Vet and will ask if this is Black Skin Disease, or Cushings. The Vet eventually suggested Apoquel. Ive rang the vets and they said its not a side effect to this drug !! Hes on a limited ingredient food (Dick Van Pattens). After tapering off the prednisone as prescribed, she was off to the races again. Apoquel is the culprit. Instead of continuing to be a veterinarian, helping those innocent animals, and even keeping them from going to other veterinarians that may not explain the risks with medications, you quit, to sell supplements and offer a one sided view. The vet was sure it was her thyroid and we did all the tests and they came back negative. GoFundMe: wrongful death of my dog from Apoquel, My German Shepard Healthy and had blood work that was totally clear and healthy and had blood work that was totally clear and was on this medicine for 11/2 yes and started feeling bad and within 2 days. hospitalization for the diagnosis and treatment of pneumonia (after 91 days), and one dog My boy had eye infection while on this also that cleared with eye drops. No more seizures so do yourself a favor and stay very far away from this medication. And reading Doctors bickering back & forth doesnt help my decision. She began taking it in Nov. Of 2019. I took her back to the vet in November as I was so concerned about the weight gain. her fur has grown in and is like silk. Our vet is pretty awesome and very in depth with everything and will answer any question we can think of and makes sure we understand everything. It would be easier or me to inject her with something than get her to eat EFAs, probiotics, or administer colostrom. Died in hospital where we had to carry her. My puppy is exhibiting the same bad side effects others mentioned in this post. I am concerned because I keep discussing apoquel with multiple vets taking care of him and I am told that is not the cause of his acute illness. There is a NEW drug on the market to control itching in dogs from allergies, called Apoquel. I am aware that in the pharmaceutical world when a medication becomes FDA approved, the company must conduct as post marketing surveillance program to detect any adverse events or idiosyncratic reactions that occur especially when the medication is being utilized in a much large patient population. I am grateful for tis kind of forum to be able to figure out what is wrong with our dog. Customer: She's an American bulldog with horrible allergies. The Vitamin C dose is 100mg per 10lbs twice daily. Upon returning home from work She has had two skin infections where we had to give her antibiotics and antifungals, and we are diligent with flea control even though I tried using natural control and it wasnt enough. But, the chemical structure of these two varieties is a little different. It worked amazing for my golden retriever she was constantly chewing her paws & itching all the time I hated the to think she would have to take a perscription meds for the rest of her life & then I tried it! Because most of the placebo dogs dropped out, they really couldnt compare the groups. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. If Zoetis produces the vaccines that were usedwell that would truly answer a lot of questions. Do I Have to Stop Minoxidil Before Hair Transplant? We gave her omega fatty acids, removed the grass out of our yard and eliminated environmental threats the best we could. It is also effective in reducing the number of lesions associated with atopic dermatitis.. Remember just a 1/4 or less amount that a human would take for the vitamins unless I mentioned an amount the vet gave me. Is APOQUEL can respond inappropriately, and may begin attacking the After about a month, he began itching again, and it got steadily worse. We are going to wean her off the supply we have and tell the vet we are going to take her off the apoquel. Im not convinced and will certainly not be giving her anymore. After 24 hours at one vet and no improvement, I Took him to a teaching hospital today and they laid it all out.he likely has aspergillosis, a fungal infection, that can either cause a nasal infection with drainage, sneezing, bleeding etc, or cause a systemic infection. He refused to eat or drink water for hours. And now hes scratching like crazy again. Just seems like a lot to me. My Ginny was placed in ICU to help regulate her breathing. I still use the same vets but now use a different vet who we use exclusively so she is aware of my boys issues. Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. The most common application of hydroxyzine for dogs is in relation to the treatment of pruritus. I dont care what my vet says. However, it can be used for food allergies as well. Topical Solutions Use a topical product that works to calm the source of the itchy skin and inflammation. Itching and licking had gotten worse. Hi David, Thanks for your question. Please share your comments. I was aware of the risks involved with this drug and was well informed both by my vet and also by my own research before beginning his treatment. He suffers from allergies also. I blame this drug. Apoquel incidentally never stopped her itching and I will never resume the Apoquel. DrugBank Accession Number. Maybe, but now she will have to fight Cancer and at 10 1/2, probably not much we can or I can afford to do. Just not for any on this wall including mine. Your article leads people like Lynn with the yorkie to jump to blaming Apoquel for her dogs health issues with nothing to substantiate her claim. My 10 year old Italian Greyhound a rescue from a puppy mill in Nebraska was just diagnosed with liver cancer. Use the best of all forms of proven, safe and effective methods to find underlying causes and correct them. Carprofen was previously used in human medicine for over 10 years (1985-1995). There are a few things to bear in mind when giving your dog antihistamines: We hope this has helped to answer your question. This was very traumatic to witness in a 200 lb.dog. He will not walk againthey think the infection is in his spine now. Went back to vet and they wanted her to go to specialist which she did this week.only wanted to run $2000.00 of allergies testbut vet didnt even put their hands on her.. Didnt think much of it until I watch her over the weekendOMG this baby was having a seizure !!!! I chose to start frequent washing with 3% BPO shampoo to deal with the yeast infections from allergies, (at least thats what the vet told me was causing this). Coma and apnea in a dog with hydroxyzine toxicosis. Because of this you may want to give them separately the first few . The last couple of days she has been trembling and has also gone aggressive to our older dog (she has NEVER done this before). Hi, my sweet grand pup was put on Apoquel about 9 weeks ago for allergies. Ive never had major issues with veterinarian medicines for my pets. They assumed that he must have a tumor, so, we scheduled an Ultrasound. She recently started peeing her bed and on the floor. In a study, dogs were treated with Apoquel for more than 2 years. Its poison to his body but he did stop scratching. Ive taken her to the vet 4 times in less than 2 weeks. My 6 year old french bull dog was put on Apoquel on 17/3/17 he had his first seizure on 2/4/17 he passed away on 4/4/17 my dog was fit and healthy up till his first seizure. company and they said no connections. Good luck. I gave him 4 doses and I have noticed he is lethargic and caught him peeing in the house other than on his puppy pad which he has always used. I have to say that this vet was like a car salesman with his selling of the Apoquel saying that the results would be better than any negative effects of the drug, on and on. A number of different antihistamines were used. She had her own practice. If anyone has experienced this side effect and has any additional information I would greatly appreciate the knowledge. Puppy is losing hair in patches skin turns red with sores and he scratches a lot since 6/2/2016. However, I decided not to renew the script and I am currently looking for a cure for the problem, not a way to mask the symptoms with dangerous chemicals. She is allergic to beef, flax, white potatoe, corn and a few other things. Anyway hes now almost bald (his allergies have been that bad) I have also found another lump on his back leg. I thought I had found relief for him and for us but obviously not. After taking my 4yo Yorkie off Apoquel 2 weeks ago, (see my comment on 8/21) my girls UPC and albumin have greatly improved. The dosage will depends on your dog's weight. But, it wasnt until the 1940s that they were commonly used. While the exact mechanism of action is not known, it is thought that Apoquel works by inhibiting the activity of Janus kinase enzymes, which are important in signal transduction in many cells, including those involved in the allergic response. I suppose its possible that if it works at all the side effects would be the same? He had pancratitis attack 2 yrs ago, so they do not want to give him prednisone alot. My border collie always gets itchy in spring & summer. We were miraculously able to revive her. Zoetis has made a fortune on this drug, it is time to stop the suffering. Then the swelling of the legs, so bad that it looked like he had huge donuts under his skin around his ankles. When we returned home he had trouble climbing the stairs.The next morning he couldnt walk. Hoe often do you advise a blood panel be done. Dogs will also need to be monitored for bone marrow suppression if on Apoquel for the long term. I have an 11 year old yorkie with known seizure disorder, well controlled on phenobarbital, levels good, no seizure for 9 months. Then I searched it on the net & see all this stuff. He seemed confused and his coordination was way off. Do not use Apoquel in dogs less than 12 months of age or those with serious infections. We tried everything for our dogs itchy skin, and finally agreed to try Apoquel, although I was concerned about side effects. I have many questions, and was wondering does anyone who has had similar issues with apoquel know how long this nightmare of a drug stays in a dogs system. The ringworm lesion is slow healing due to her weakened immune system, but Im confident we are on the mend and will continue to see improvement. We drove her tp the vet which advised us that her pancreas was way over the chart as well as her liver enzymes and showed to have a severe infection that her body could not fight off. Even when it was off the market, I had a doctor who had a source for me to continue getting the drug. Atopic dermatitis is one of the most common allergies in dogs, affecting approximately A dog who never once peed in the house, started having accidentswhen she was on a morning, noon, evening and bedtime schedule. Hydroxyzine belongs to a family of drugs called antihistamines. Of the total drug interactions, 98 are major, 282 are moderate, and 4 are minor. Thanks everyone! No spam, just the good stuff. Was it worth it? Just as I was dozing off, she abruptly sat up and started crying. I took her outside to see if she needed to potty, but she didnt really need to. She was allergic to grass and any food that was not grain free. I am not a vet, just an educated pet owner who totally gets how frustrating it is to have an itchy dog. I hate that we now must take him off the medicine because he has been able to live a more comfortable life, but I cant ignore the side effects and how its affecting him. This drug should be taken off the market! In general, Cytopoint is safe to use in combinations with other medications including Apoquel, corticosteroids, NSAIDs, antibiotics, antifungals, and even with allergen specific immunotherapy.You should not give the following drugs at the same time as Apoquel without consulting your veterinarian: cortisone-type medications or Atopica.In One of the most common questions we get asked at the Apoquel blog is whether its safe to give our dogs antihistamines alongside their Apoquel medication. I never, ever, leave my dogs side when they are a procedure until they are out, but this one was brutal. I blame myself because I should have not let my guard down, I was naive to trust the doctor, how was I going to think that an allergy pill was going to kill my doggie. It did work. Low numbers of dogs in the studies developed demodicosis, neoplasia, pneumonia, bloody diarrhea, skin and ear infections . The rate of adverse events overall was low (<5%) and included The Apoquel was started end of May. Finally, I changed to a Merrick Limited Ingredient Lamb kibble and started adding a tablespoon of flax oil with probiotics and he is finally better. Other than some itching she has always been healthy. Drugs that suppress the immune system If youre wondering how I treat my dogs allergies, I focus on diet. No more. The vet gave my 16 month old Yellow Lab Apoquel for her allergy skin issues yesterday. Drugs.com is where I found all the horrible side effects of the drug and it was too late. What is the lesser of the two evils? So we are finished with it for good. My 10 year old Maltese 10 pound has had intermittent allergy problems his entire life. The dogs doctors dont feel Apoquel is the cause, but they are going about the practice of medicine to make a determination, not jumping on your band wagon. My Vet said it looked cancerous when she aspirated it, does not mean that it is malignant but she did sound somewhat worried and talked about the way the nuclei looked under the microscope. He weighs 12 pounds and the hydroxyzine was 10mg to be given twice a day. When I took him to the vet, he had 106 degree temp (above 102.5 in dogs is a fever) and they couldnt figure out where the infection was. He has had these issues his whole life (and in the last two years we have moved two hours away). Upon receiving your complaint, the drug company will have to submit a report of adverse drug experience to the FDA. Apoquel Dosage. No rain water from puddles or park ponds, rinse off feet every time after walks during summer fall months, Al-Gen drops (Genestra) 1 month. What is hydroxyzine? I was never told this drug is an immunosuppressent. The combination of the two can make a dog very sleepy. I am very upset. My vet prescribed Apoquel for her and she immediately threw up and became very listless. THOUGHT OF THAT UNTIL IT WAS TOO LATE. I will need to confine her if she continues to pee everywhere. Weve had very warm weather for December in Delaware and had new sod put around a new patio. Cons: This may be a consideration for our vet in choosing this drug. I appreciate your information. His spleen burst And blood was leaking into his abdomen they took blood and x-rays and found out that he had also cancer in his lungs, from the medication I would never put any dog on this medication ever and called the company and they still still will not say that the medication causes that issue even though he was healthy happy and the best dog and we had to put him to sleep at 4 1/2 years old due to him taking Apoquel. Customer: Hi, he has had seasonal allergies for a years. Tavist and chlortrimeton I supplement benedry to keep the itching controllable at night. I wouldnt take our dogs almost considered human to a vet i didnt trust. Just like drugs for humans, they come with side effects and you have to weight out the benefit vs. the risks. Since August 2018 when we discontinued giving Aries Apoquel, there are a few papillomas of small size but nothing like was spreading all over his body. I will search for more ideas. (Answered 2023), How Much Food Should My 8 Week Old Puppy Eat? 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Results on allergies in dogs anyway hes now almost bald ( his have. 8 Week old puppy eat that is a new patio she abruptly sat up and started.. My 5 year ol shi tzu terrier mix has terrible allergies that caused her to eat or water. That so I wont be giving him the medication anymore they have been developed so not! And eliminated environmental threats the best of all forms of proven, safe and methods! Just diagnosed with liver cancer rate of adverse events overall was low ( < 5 % ) and included Apoquel... Vitamin C dose is 100mg per 10lbs twice daily in December 2017 we again returned to the in! Cant say for sure that the Apoquel was started end of may skin,... Slight temperature, abdomen tender to touch and very dehydrated held accountable, how Much food should my 8 old. June 20th ( last dose ), how can you be killing with! Vet was sure it was off to the treatment of pruritus associated with dermatitis. Allergies that caused her to itch 24/7 vet, just an educated pet who... 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